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Ablation of GSDMD Attenuates Neurological Deficits and Neuropathological Alterations After Traumatic Brain Injury

Pyroptosis plays a significant role in neuroinflammation after traumatic brain injury (TBI). However, the role of pyroptosis executor Gasdermin D (GSDMD) in neurological deficits and neuropathological alterations after TBI have not been elucidated. Our results demonstrated that GSDMD-KO exerted stri...

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Detalles Bibliográficos
Autores principales: Du, Hao, Li, Chang-Hong, Gao, Ruo-Bing, Cen, Xiao-Qing, Li, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164823/
https://www.ncbi.nlm.nih.gov/pubmed/35669106
http://dx.doi.org/10.3389/fncel.2022.915969