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IMMU-02. Targeted innovative antibody fragment-based immunotherapy for medulloblastoma

Medulloblastoma (MB) is the most common malignant pediatric brain tumor accounting for ~20 % of childhood brain tumors. One third of all MB are characterized by constitutive activation of the Sonic Hedgehog (SHH)-signaling pathway. This tumor type shows overexpression of the epidermal growth-factor...

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Detalles Bibliográficos
Autores principales: Niesen, Judith, Krüger, Christina, Kreuter, Naomé, Haferkamp, Undine, Pless, Ole, Schüller, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164860/
http://dx.doi.org/10.1093/neuonc/noac079.295