HGG-21. Oncogenic tyrosine kinase gene fusions in infant-type hemispheric gliomas - comparison of RNA- and DNA-based methods for their reliable detection

High-grade diffuse gliomas (HGG) in early childhood are characterized by a more favorable outcome compared to older children. We demonstrated in previous studies that these tumors have stable genomes. Activating tyrosine kinase gene fusions in infant-type hemispheric gliomas represent therapeutic ta...

Descripción completa

Detalles Bibliográficos
Autores principales: Pietsch, Torsten, Gielen, Gerrit, Waha, Andreas, Doerner, Evelyn, von Bueren, Andre O, Vokuhl, Christian, Kristiansen, Glen, Kramm, Christof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
High Grade Glioma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164882/
http://dx.doi.org/10.1093/neuonc/noac079.236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164882/
http://dx.doi.org/10.1093/neuonc/noac079.236

Ejemplares similares