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MEDB-59. A draft atlas of medulloblastoma cellular evolution under therapy

How standard care shapes the cellular composition of recurrent medulloblastoma (MB), if therapy selects for specific tumor or immune cell types, is unknown. We report the pilot phase of our ongoing effort to profile human longitudinal MB specimens via single-cell transcriptomics and epigenetics. We...

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Detalles Bibliográficos
Autores principales: Wang, Lin, Jung, Jangham, Babikir, Husam, Shamardani, Karin, Kasahara, Noriyuki, Müller, Sabine, Diaz, Aaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164900/
http://dx.doi.org/10.1093/neuonc/noac079.433