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MEDB-50. Assessment of cellular radiosensitivity and DNA repair in medulloblastoma cell lines and patient-derivded xenograft slice cultures

Medulloblastoma (WHO grade 4) is the most common malignant brain tumor of childhood. Despite the high importance of radiotherapy for disease control, the mechanisms underlying response and resistance to radiotherapy are incompletely understood. Therefore, we assessed the radiosensitivity and DNA rep...

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Detalles Bibliográficos
Autores principales: Feyerabend, Simon, Rieckmann, Thorsten, Riepen, Britta, Oetting, Agnes, Christiansen, Sabrina, Schoof, Melanie, Hardt, Annika, Köcher, Sabrina, Neumann, Julia, Schwarz, Rudolf, Mack, Norman, Schwalm, Benjamin, Federico, Aniello, Milde, Till, Kool, Marcel, Schüller, Ulrich, Rutkowski, Stefan, Petersen, Cordula, Rothkamm, Kai, Mynarek, Martin, Struve, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164929/
http://dx.doi.org/10.1093/neuonc/noac079.424