Cargando…
MEDB-50. Assessment of cellular radiosensitivity and DNA repair in medulloblastoma cell lines and patient-derivded xenograft slice cultures
Medulloblastoma (WHO grade 4) is the most common malignant brain tumor of childhood. Despite the high importance of radiotherapy for disease control, the mechanisms underlying response and resistance to radiotherapy are incompletely understood. Therefore, we assessed the radiosensitivity and DNA rep...
Autores principales: | Feyerabend, Simon, Rieckmann, Thorsten, Riepen, Britta, Oetting, Agnes, Christiansen, Sabrina, Schoof, Melanie, Hardt, Annika, Köcher, Sabrina, Neumann, Julia, Schwarz, Rudolf, Mack, Norman, Schwalm, Benjamin, Federico, Aniello, Milde, Till, Kool, Marcel, Schüller, Ulrich, Rutkowski, Stefan, Petersen, Cordula, Rothkamm, Kai, Mynarek, Martin, Struve, Nina |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164929/ http://dx.doi.org/10.1093/neuonc/noac079.424 |
Ejemplares similares
-
MEDB-41. Identifying a subgroup of patients with early childhood sonic hedgehog-activated medulloblastoma with unfavorable prognosis after treatment with radiation-sparing regimens including intraventricular methotrexate
por: Tonn, Svenja, et al.
Publicado: (2022) -
MEDB-37. Chemotherapy response prediction by molecular risk factors in metastatic childhood medulloblastoma
por: Obrecht, Denise, et al.
Publicado: (2022) -
MEDB-51. Impact of residual tumor on outcomes in children and adolescents with medulloblastoma in the German HIT-cohort
por: Wolgast, Stella, et al.
Publicado: (2022) -
MEDB-52. Organoids as preclinical models to improve and personalize disease outcome for sonic hedgehog medulloblastoma
por: Odé, Zelda, et al.
Publicado: (2022) -
MEDB-36. Clinical and molecular heterogeneity withinMYC andMYCN amplified medulloblastoma
por: Schwalbe, Edward, et al.
Publicado: (2022)