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DIPG-21. DIPG cells alter the permeability of the blood-brain barrier in the brainstem leading to treatment failure.

Diffuse Intrinsic Pontine Glioma (DIPG) is an aggressive paediatric high-grade glioma with no effective therapies. The blood-brain barrier (BBB) presents a significant obstacle for delivery of therapeutics into the brain, especially in the brainstem. This study aims to investigate the effect of DIPG...

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Detalles Bibliográficos
Autores principales: Ung, Caitlin, Upton, Dannielle H, Venkat, Pooja, Pandher, Ruby, Curnis, Flavio, Corti, Angelo, Nicolazzo, Joesph, Mayoh, Chelsea, Tsoli, Maria, Ziegler, David S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164937/
http://dx.doi.org/10.1093/neuonc/noac079.078