MEDB-33. The landscape of ecDNA in medulloblastoma

Extrachromosomal circular DNA (ecDNA) is an important driver of aggressive cancers, including medulloblastoma (MB), the most common malignant pediatric brain tumor. To assess the clinical importance of ecDNA in MB, we applied computational methods to detect ecDNA in the genomes of a cohort of 468 MB...

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Detalles Bibliográficos
Autores principales: Chapman, Owen, Sridhar, Sunita, Wang, Shanqing, Larson, Jon, Wechsler-Reya, Robert, Mesirov, Jill, Chavez, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Medulloblastoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164941/
http://dx.doi.org/10.1093/neuonc/noac079.407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164941/
http://dx.doi.org/10.1093/neuonc/noac079.407

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