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MEDB-33. The landscape of ecDNA in medulloblastoma
Extrachromosomal circular DNA (ecDNA) is an important driver of aggressive cancers, including medulloblastoma (MB), the most common malignant pediatric brain tumor. To assess the clinical importance of ecDNA in MB, we applied computational methods to detect ecDNA in the genomes of a cohort of 468 MB...
Autores principales: | Chapman, Owen, Sridhar, Sunita, Wang, Shanqing, Larson, Jon, Wechsler-Reya, Robert, Mesirov, Jill, Chavez, Lukas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164941/ http://dx.doi.org/10.1093/neuonc/noac079.407 |
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