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LGG-45. Genetic dependencies inMYB/MYBL1-driven pediatric low-grade glioma models

AIM: Pediatric low-grade gliomas (pLGGs) are a heterogenous group of tumors, diverse in their localization, histology, mutational landscape, clinical behavior, and treatment response. Genomic alterations impacting the MYB family of transcription factors were identified in two distinct pLGG subtypes:...

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Detalles Bibliográficos
Autores principales: Condurat, Alexandra-Larisa, Jones, Jill, Gonzalez, Elizabeth, Doshi, Jeyna, Zhou, Kevin, Tsai, Jessica W, Khadka, Prasidda, Buchan, Graham B J, Rouleau, Cecile, Pelton, Kristine, Abid, Tanaz, Goodale, Amy, Persky, Nicole, Beroukhim, Rameen, Ligon, Keith, Root, David, Piccioni, Federica, Bandopadhayay, Pratiti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164946/
http://dx.doi.org/10.1093/neuonc/noac079.357