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LGG-45. Genetic dependencies inMYB/MYBL1-driven pediatric low-grade glioma models
AIM: Pediatric low-grade gliomas (pLGGs) are a heterogenous group of tumors, diverse in their localization, histology, mutational landscape, clinical behavior, and treatment response. Genomic alterations impacting the MYB family of transcription factors were identified in two distinct pLGG subtypes:...
Autores principales: | Condurat, Alexandra-Larisa, Jones, Jill, Gonzalez, Elizabeth, Doshi, Jeyna, Zhou, Kevin, Tsai, Jessica W, Khadka, Prasidda, Buchan, Graham B J, Rouleau, Cecile, Pelton, Kristine, Abid, Tanaz, Goodale, Amy, Persky, Nicole, Beroukhim, Rameen, Ligon, Keith, Root, David, Piccioni, Federica, Bandopadhayay, Pratiti |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164946/ http://dx.doi.org/10.1093/neuonc/noac079.357 |
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