MODL-04. Drug screening in Disorders with Abnormal DNA Damage Response/Repair (DADDR) andin vivo validation

INTRODUCTION: Disorders with Abnormal DNA Damage Response/Repair (DADDRs) are inherited conditions caused by constitutional mutations of DNA damage response and repair genes and are characterized by an increased cancer risk. Furthermore, affected individuals also show an elevated risk of secondary n...

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Detalles Bibliográficos
Autores principales: Kolodziejczak, Anna, Selt, Florian, Peterziel, Heike, Jamaladdin, Nora, Mack, Norman, Maass, Kendra, Kool, Marcel, Herold-Mende, Christel, El Damaty, Ahmed, Oehme, Ina, Jones, David T W, Witt, Olaf, Pajtler, Kristian W, Kratz, Christian, Pfister, Stefan M, Milde, Till
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Preclinical Models/Experimental Therapy/Drug Discovery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164948/
http://dx.doi.org/10.1093/neuonc/noac079.627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164948/
http://dx.doi.org/10.1093/neuonc/noac079.627

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