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ATRT-13. An integrative analysis of the ATRT proteome unravels novel drug targets and refines molecular subgrouping

INTRODUCTION: Atypical teratoid/rhabdoid tumors (ATRT) represent frequent brain tumors in infants. In recent years, large-scale landscaping efforts on the epigenome and transcriptome of these tumors have unravelled a high degree of heterogeneity and three major molecular subgroups, termed ATRT-TYR,...

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Detalles Bibliográficos
Autores principales: Johann, Pascal, Müller, Torsten, Kalxdorf, Mathias, Hasselblatt, Martin, Frühwald, Michael C, Pfister, Stefan M, Krijgsveld, Jeroen, Kool, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164949/
http://dx.doi.org/10.1093/neuonc/noac079.012