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ATRT-13. An integrative analysis of the ATRT proteome unravels novel drug targets and refines molecular subgrouping
INTRODUCTION: Atypical teratoid/rhabdoid tumors (ATRT) represent frequent brain tumors in infants. In recent years, large-scale landscaping efforts on the epigenome and transcriptome of these tumors have unravelled a high degree of heterogeneity and three major molecular subgroups, termed ATRT-TYR,...
Autores principales: | Johann, Pascal, Müller, Torsten, Kalxdorf, Mathias, Hasselblatt, Martin, Frühwald, Michael C, Pfister, Stefan M, Krijgsveld, Jeroen, Kool, Marcel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164949/ http://dx.doi.org/10.1093/neuonc/noac079.012 |
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