MODL-27. An organotypic brain slice culture platform as a novel pre-clinical model for diffuse intrinsic pontine glioma and diffuse midline glioma

High-grade pediatric brain tumors (PBTs) such as diffuse intrinsic pontine glioma (DIPG) and diffuse midline glioma (DMG) are devastating diseases with a median survival of just 11 months. Little progress has been made in identifying effective treatments due to the lack of effective pre-clinical mod...

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Detalles Bibliográficos
Autores principales: Mann, Breanna, Zhang, Xiaopei, Bell, Noah, Adefolaju, Adebimpe, Dasari, Rajaneekar, Valdivia, Alain, Buckley, Andrew, Quinsey, Carolyn, Hingtgen, Shawn, Satterlee, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Preclinical Models/Experimental Therapy/Drug Discovery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164960/
http://dx.doi.org/10.1093/neuonc/noac079.650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164960/
http://dx.doi.org/10.1093/neuonc/noac079.650

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