Cargando…

MODL-27. An organotypic brain slice culture platform as a novel pre-clinical model for diffuse intrinsic pontine glioma and diffuse midline glioma

High-grade pediatric brain tumors (PBTs) such as diffuse intrinsic pontine glioma (DIPG) and diffuse midline glioma (DMG) are devastating diseases with a median survival of just 11 months. Little progress has been made in identifying effective treatments due to the lack of effective pre-clinical mod...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mann, Breanna, Zhang, Xiaopei, Bell, Noah, Adefolaju, Adebimpe, Dasari, Rajaneekar, Valdivia, Alain, Buckley, Andrew, Quinsey, Carolyn, Hingtgen, Shawn, Satterlee, Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Preclinical Models/Experimental Therapy/Drug Discovery
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164960/ http://dx.doi.org/10.1093/neuonc/noac079.650

Ejemplares similares

MODL-12. DEVELOPMENT OF A NOVEL IMMUNOCOMPETENT MOUSE MODEL FOR DIFFUSE INTRINSIC PONTINE GLIOMA
por: Seblani, Maggie, et al.
Publicado: (2020)

MODL-29. EVALUATING TUMOR-IMMUNE INTERACTIONS IN MOUSE MODELS OF DIFFUSE INTRINSIC PONTINE GLIOMA
por: Furnish, Robin, et al.
Publicado: (2020)

MODL-24. AN ORGANOTYPIC CHUNK CULTURE TECHNIQUE TO STUDY DISEASE MECHANISM AND DEVELOP TARGETED THERAPEUTICS FOR PEDIATRIC ADAMANTINOMATOUS CRANIOPHARYNGIOMA
por: Vijmasi, Trinka, et al.
Publicado: (2020)

EPID-15. THE INTERNATIONAL DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)/DIFFUSE MIDLINE GLIOMA (DMG) REGISTRY AND REPOSITORY (IDIPGR) EXPANSION
por: Torontali, Marianne, et al.
Publicado: (2020)

A Protocol for the Generation of Treatment-naïve Biopsy-derived Diffuse Intrinsic Pontine Glioma and Diffuse Midline Glioma Models
por: Biery, Matt C., et al.
Publicado: (2020)

MODL-06. Targeting c-MET in combination with radiation is effective in MET-fusion driven high-grade glioma
por: Zuckermann, Marc, et al.
Publicado: (2022)

MODL-31. Novel in vivo models of post-radiation recurrent pediatric high-grade glioma show increased susceptibility to MAPK inhibition
por: Knox, Aaron, et al.
Publicado: (2022)

Therapeutic targeting of prenatal pontine ID1 signaling in diffuse midline glioma
por: Messinger, Dana, et al.
Publicado: (2022)

Infusion-related side-effects during convection enhanced delivery for brainstem-diffuse midline glioma/diffuse intrinsic pontine glioma
por: Hollingworth, Milo, et al.
Publicado: (2022)

MODL-17. SHP2 INHIBITORS SHOW ACTIVITY AGAINST NF1-DEFICIENT GLIOMAS AND ENHANCE MAPK PATHWAY INHIBITION IN BRAF-V600E MUTANT GLIOMAS
por: Muldoon, Daniel, et al.
Publicado: (2020)

OTHR-05. A LIVING EX VIVO PLATFORM FOR FUNCTIONAL, PERSONALIZED PEDIATRIC BRAIN CANCER DIAGNOSIS
por: Mann, Breanna, et al.
Publicado: (2023)

MODL-31. RADIATION-DERIVED TREATMENT-RESISTANT PDX AND CELL CULTURE MODELS RECAPITULATE THE CHARACTERISTICS OF MATCHED PRIMARY/RECURRENT PEDIATRIC HIGH-GRADE GLIOMA
por: Knox, Aaron J, et al.
Publicado: (2020)

BIOL-14. FROM NON-MALIGNANT TO MALIGNANT: GENERATING AND TARGETING DIFFUSE MIDLINE GLIOMA IN A NOVEL HUMAN PONTINE ORGANOID MODEL
por: Bessler, Nils, et al.
Publicado: (2023)

MODL-20. A BIOBANK OF ~100 PATIENT-DERIVED MODELS REPRESENTING BIOLOGICAL HETEROGENEITY AND DISTINCT THERAPEUTIC DEPENDENCIES IN PAEDIATRIC HIGH GRADE GLIOMA AND DIPG
por: Carvalho, Diana, et al.
Publicado: (2020)

A living ex vivo platform for functional, personalized brain cancer diagnosis
por: Mann, Breanna, et al.
Publicado: (2023)

BIOL-19. DIFFUSE MIDLINE GLIOMA CEREBRAL ORGANOID MODEL AND MULTIOMICS CHARACTERIZATION
por: Damodharan, Sudarshawn, et al.
Publicado: (2023)

Diffuse intrinsic pontine glioma: poised for progress
por: Warren, Katherine E.
Publicado: (2012)

Nanotechnology Applications for Diffuse Intrinsic Pontine Glioma
por: Bredlau, Amy Lee, et al.
Publicado: (2017)

Genomic Insights into Diffuse Intrinsic Pontine Glioma
por: Lapin, Danielle H., et al.
Publicado: (2017)

MODL-02. TARGETING REPLICATION STRESS IN PEDIATRIC BRAIN TUMORS
por: Krausert, Sonja, et al.
Publicado: (2020)

MODL-11. COMPARISON OF HUMAN & MURINE PA/PXA CHARACTERISTICS
por: Sommerkamp, Alexander C, et al.
Publicado: (2020)

MODL-01. Targeting replication stress in pediatric brain tumors
por: Krausert, Sonja, et al.
Publicado: (2022)

IMMU-14. SynNotch chimeric antigen receptor (CAR) T-cells as a potential treatment for diffuse intrinsic pontine glioma (DIPG)/diffuse midline glioma (DMG)
por: Ferrerosa, Lauren, et al.
Publicado: (2022)

Pediatric Diffuse Midline Gliomas: An Unfinished Puzzle
por: Di Ruscio, Valentina, et al.
Publicado: (2022)

Immunotherapy approaches for the treatment of diffuse midline gliomas
por: Bernstock, Joshua D., et al.
Publicado: (2022)

Interdisciplinary care of children with diffuse midline glioma
por: Coleman, Christina, et al.
Publicado: (2022)

The promise of metabolic imaging in diffuse midline glioma
por: Lovibond, Samantha, et al.
Publicado: (2023)

MODL-28. IMMUNE PRIMING WITH INTERFERON-Γ COMBINED WITH EPIGENETIC MODULATION IN PEDIATRIC BRAIN TUMORS
por: Crotty, Erin, et al.
Publicado: (2020)

Diffusion Tensor Histogram Analysis of Pediatric Diffuse Intrinsic Pontine Glioma
por: Steffen-Smith, Emilie A., et al.
Publicado: (2014)

MODL-01. SAFETY IN CONCOMITANT USE OF MEK AND BRAF INHIBITORS WITH BEVACIZUMAB
por: Winzent, Shelby, et al.
Publicado: (2020)

MODL-06. PRECLINICAL EFFICACY OF THE IMIPRIDONE ONC-206 AGAINST MEDULLOBLASTOMA
por: Malhotra, Anshu, et al.
Publicado: (2020)

CNSC-01. GABAERGIC NEURON-TO-GLIOMA SYNAPSES IN DIFFUSE MIDLINE GLIOMAS
por: Barron, Tara, et al.
Publicado: (2023)

TRLS-06. A PHASE 1, SAFETY AND DOSE ESCALATION STUDY OF BXQ-350 IN COMBINATION WITH RADIATION IN PEDIATRIC PATIENTS WITH DIFFUSE MIDLINE GLIOMA OR DIFFUSE INTRINSIC PONTINE GLIOMA
por: Dorris, Kathleen, et al.
Publicado: (2023)

Pre-Clinical Models of Diffuse Intrinsic Pontine Glioma
por: Misuraca, Katherine L., et al.
Publicado: (2015)

Epigenetic Targeted Therapy for Diffuse Intrinsic Pontine Glioma
por: HASHIZUME, Rintaro
Publicado: (2017)

Hypofractionated radiotherapy in children with diffuse intrinsic pontine glioma
por: Hayashi, Akiko, et al.
Publicado: (2020)

Immune Microenvironment and Immunotherapies for Diffuse Intrinsic Pontine Glioma
por: Chen, Yujia, et al.
Publicado: (2023)

Radiotherapy for Diffuse Intrinsic Pontine Glioma: Insufficient but Indispensable
por: Kim, Hyun Ju, et al.
Publicado: (2023)

Epigenetic and Metabolic Changes in Diffuse Intrinsic Pontine Glioma
por: Park, Jiyoon, et al.
Publicado: (2023)

MODL-30. DISSECTING THE ROLE OF MULTI-CILIOGENESIS NETWORK IN CHOROID PLEXUS TUMOR
por: Zhao, Haotian, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_usqlidjofu2camcfq4ods56nt1