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EPEN-25. A novel spontaneous model of ZFTA-RELA fusion ependymoma

Ependymomas driven by the ZFTA-RELA fusion account for >70% of all supratentorial ependymomas. These tumours are now recognised in the WHO classification of CNS tumours and have been associated with a poor prognosis. Seven ZFTA-RELA fusion variants have been described: around two thirds of cases...

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Detalles Bibliográficos
Autores principales: Bell, Sigourney, King, Claire, Rahrmann, Katherine Wickham, Jassim, Amir, Taylor, Jessica, Gilbertson, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164965/
http://dx.doi.org/10.1093/neuonc/noac079.161