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DIPG-45. Radiation induces a robust interferon response in Diffuse Midline Glioma (DMG), improving the potential for combination immunotherapy

Diffuse Midline Glioma (DMG), H3K27M altered, confers a dismal survival of 9-15 months and has a non-inflammatory tumor immune microenvironment (TIME). Radiation therapy (RT) is the mainstay treatment for DMG and has been shown in other cancers to recruit an immune component. However, the effect of...

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Detalles Bibliográficos
Autores principales: Minns, Hanna E, Padilla, Oscar, Wei, Hong-Jian, Webster-Carrion, Andrea, Tazhibi, Masih, McQuillan, Nicholas, Zhang, Xu, Yeh, Rebecca, Zhang, Zhiguo, Szalontay, Luca, Pavisic, Jovana, Garty, Guy, Garvin, James, Zacharoulis, Stergios, Canoll, Peter, Vanpouille-Box, Claire I, Menon, Vilas, Olah, Marta, Rabadan, Raul, Wu, Cheng-Chia, Gartrell, Robyn D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164968/
http://dx.doi.org/10.1093/neuonc/noac079.102