LGG-50. Human induced pluripotent stem cell engineering establishes a humanized mouse platform for pediatric low-grade glioma modeling

A major obstacle to identifying improved treatments for pediatric low-grade brain tumors (gliomas) is the inability to reproducibly generate human xenografts. To surmount this barrier, we leveraged human induced pluripotent stem cell (hiPSC) engineering to generate low-grade glioma (LGG) lesions rep...

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Detalles Bibliográficos
Autores principales: Anastasaki, Corina, Chatterjee, Jit, Cobb, Olivia, Scheaffer, Suzanne, Sanapala, Shilpa, Costa, Amanda, Wilson, Anna, Garbow, Joel, Rodriguez, Fausto, Gutmann, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Low Grade Glioma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164989/
http://dx.doi.org/10.1093/neuonc/noac079.362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164989/
http://dx.doi.org/10.1093/neuonc/noac079.362

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