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MEDB-87. Transcriptome-driven drug repurposing in group 3 medulloblastoma

Across the molecular spectrum of medulloblastoma (MB), group 3 (G3) tumors are the most aggressive with <50% five-year survival, the lowest of all MB subgroups. G3 MB tumors are characterized by frequent metastases at diagnosis, unique methylation profiles, MYC amplification, and i17q, but these...

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Detalles Bibliográficos
Autores principales: Doss, David, Kanchan, Ranjana, Perumal, Naveenkumar, Batra, Surinder, Mahapatra, Sidharth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165013/
http://dx.doi.org/10.1093/neuonc/noac079.461