MEDB-45. Functional genomics identifies epigenetic regulators as novel therapeutic targets for sonic hedgehog medulloblastoma

Medulloblastoma (MB) is among the most common malignant childhood brain tumors that comprises a group of four molecularly distinct diseases. A significant proportion of these tumors is characterized by aberrant activation of the canonical sonic hedgehog (SHH) signaling pathway. Although small-molecu...

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Detalles Bibliográficos
Autores principales: Tsiami, Foteini, Piccioni, Federica, Root, David, Bandopadhayay, Pratiti, Segal, Rosalind, Tabatabai, Ghazaleh, Merk, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Medulloblastoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165027/
http://dx.doi.org/10.1093/neuonc/noac079.419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165027/
http://dx.doi.org/10.1093/neuonc/noac079.419

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