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IMG-09. Characterisation of a panel ofin vivo models of paediatric-type diffuse high-grade glioma (PDHGG) using magnetic resonance imaging

Novel therapies for paediatric-type diffuse high-grade glioma (PDHGG) are urgently required. Orthotopic models using patient-derived material are invaluable tools in preclinical drug development as they retain key genetic/epigenetic features, eg. histone H3G34 or H3K27 alterations. Their evaluation...

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Detalles Bibliográficos
Autores principales: Boult, Jessica, Carvalho, Diana, Kessler, Ketty, Vinci, Maria, Fernandez, Elisabet, Bjerke, Lynn, Fofana, Mariama, Molinari, Valeria, Carcaboso, Angel, Jones, Chris, Robinson, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165046/
http://dx.doi.org/10.1093/neuonc/noac079.285