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IMG-09. Characterisation of a panel ofin vivo models of paediatric-type diffuse high-grade glioma (PDHGG) using magnetic resonance imaging
Novel therapies for paediatric-type diffuse high-grade glioma (PDHGG) are urgently required. Orthotopic models using patient-derived material are invaluable tools in preclinical drug development as they retain key genetic/epigenetic features, eg. histone H3G34 or H3K27 alterations. Their evaluation...
Autores principales: | Boult, Jessica, Carvalho, Diana, Kessler, Ketty, Vinci, Maria, Fernandez, Elisabet, Bjerke, Lynn, Fofana, Mariama, Molinari, Valeria, Carcaboso, Angel, Jones, Chris, Robinson, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165046/ http://dx.doi.org/10.1093/neuonc/noac079.285 |
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