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ATRT-12. LIN28A expression correlates with poor prognosis and the MYC subgroup in AT/RTs

Atypical teratoid/rhabdoid tumors (AT/RTs) are malignant embryonal tumors of the central nervous system, which mainly affect young children. These tumors are defined by loss of SMARCB1 (or SMARCA4 in rare cases) and can be categorized into three main DNA methylation subgroups (i.e. –MYC, -SHH, -TYR)...

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Detalles Bibliográficos
Autores principales: Dottermusch, Matthias, Brakopp, Sina, Struve, Nina, Frühwald, Michael C, Merk, Daniel J, Tabatabai, Ghazaleh, Schüller, Ulrich, Hasselblatt, Martin, Neumann, Julia E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165049/
http://dx.doi.org/10.1093/neuonc/noac079.011