HGG-03. PEDIATRIC BITHALAMIC GLIOMA H3K27M NEGATIVE AND EGFR POSITIVE: A DISTINCT ENTITY WITH POTENTIAL SENSIBILITY TO EGFR INHIBITORS

INTRODUCTION: Brain tumors are the most common solid tumors of childhood and optimal therapeutic strategies for many subtypes remain unknown. Bithalamic gliomas, in contrast with unilateral, have frequent mutations in the EGFR oncogene and only rare Histone H3 mutation. These EGFR mutations are smal...

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Detalles Bibliográficos
Autores principales: Hernandez, Marta Cortes, Schiaffino, Guiomar Gutierrez, Almeida, Silvia Torrejon, MoroñO, Sara Iglesias, Lara, Bernardo Weil, Leon, Maria Isabel Martinez, Alvarez, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
High Grade Glioma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165050/
http://dx.doi.org/10.1093/neuonc/noac079.219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165050/
http://dx.doi.org/10.1093/neuonc/noac079.219

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