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HGG-08. Lorlatinib for the treatment of ALK fusion positive infant high grade glioma

BACKGROUND: High grade gliomas (HGG) are very rare in the infant age group with approximately 800 cases diagnosed in the USA and Europe each year. Histologically, HGG in infants resemble HGG in older children and adults but have distinct molecular features like ALK, NTRK, MET and ROS1 fusions. HGG i...

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Detalles Bibliográficos
Autores principales: Greenwell, Alyssa, Altinok, Deniz, Marupudi, Neena, Kupsky, William, Gorsi, Hamza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165068/
http://dx.doi.org/10.1093/neuonc/noac079.223