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INSP-09. Using genetically engineered mouse models and patient-derived orthotopic xenografts to develop new therapies for pediatric brain tumors.

Medulloblastoma is the most common malignant pediatric brain tumor. Extensive molecular analysis by many groups around the world demonstrated four distinct subgroups, WNT, SHH, Group3 and Group4 that now all have been divided into 11 total subtypes, 8 for Grou3 and Group4 medulloblastoma. SHH with M...

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Detalles Bibliográficos
Autores principales: Jonchere, Barbara, Pribnow, Allison, Morfouace, Marie, Shelat, Anang, Yu, Jiyang, Rankovic, Zoran, Gajjar, Amar, Northcott, Paul A, Robinson, Giles W, Roussel, Martine F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165082/
http://dx.doi.org/10.1093/neuonc/noac079.705