MODL-31. Novel in vivo models of post-radiation recurrent pediatric high-grade glioma show increased susceptibility to MAPK inhibition

BACKGROUND: Pediatric high-grade glioma (pHGG) is the most common cause of childhood cancer mortality, with median survival of less than one year. The standard of care for pHGG includes radiation therapy (RT), but almost all patients who respond initially relapse with aggressive, radiation-resistant...

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Detalles Bibliográficos
Autores principales: Knox, Aaron, DeSisto, John, Nelson-Taylor, Sarah, Coleman, Philip, Van Court, Benjamin, Donson, Andrew, Karam, Sana, Green, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Preclinical Models/Experimental Therapy/Drug Discovery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165087/
http://dx.doi.org/10.1093/neuonc/noac079.654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165087/
http://dx.doi.org/10.1093/neuonc/noac079.654

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