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MEDB-39. Oncogenic mechanisms underlying GLI2-amplified medulloblastoma

Medulloblastoma (MB) is the most common malignant brain tumor in children. There are several subtypes of MB, and among them, the subtype of GLI2-amplified SHH-MB associated with P53 mutations has the worst prognosis and a poor survival rate; the 5-year survival rate is <30%. Moreover, the GLI2-am...

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Detalles Bibliográficos
Autores principales: Murad, Najiba, Zhang, Jiao, Liu, Xiao, Tao, Ran, Taylor, Michael, Pei, Yanxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165099/
http://dx.doi.org/10.1093/neuonc/noac079.413