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ETMR-02. Overexpression of Lin28A in neural progenitor cells in vivo does not lead to brain tumor formation but results in reduced spine density

The RNA binding protein LIN28A is a stem- and progenitor marker and one of the factors necessary to induce pluripotent stem cells. An overexpression of LIN28A has been identified in malignant brain tumors called embryonal tumors with multilayered rosettes (ETMR) but its specific role during brain de...

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Detalles Bibliográficos
Autores principales: Middelkamp, Maximilian, Ruck, Lisa, Krisp, Christoph, Sumislawski, Piotr, Mohammadi, Behnam, Dottermusch, Matthias, Meister, Valerie, Küster, Lukas, Schlüter, Hartmut, Windhorst, Sabine, Neumann, Julia E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165115/
http://dx.doi.org/10.1093/neuonc/noac079.180