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IMMU-10. TUMOR ASSOCIATED MYELOID CELLS DRIVE THE IMMUNOBIOLOGY OF HIGH RISK PEDIATRIC EPENDYMOMA

Molecular profiling of pediatric ependymoma (EPN) has previously identified discrete neoplastic subpopulations, of which Mesenchymal EPN Cells (MEC) characterize Posterior Fossa A tumors (PFA). MECs are associated with tumor immunosuppression. Here we further characterize the EPN immune environment...

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Detalles Bibliográficos
Autores principales: Griesinger, Andrea, Riemondy, Kent, Eswaran, Nithyashri, Donson, Andrew, Willard, Nicholas, Paine, Simon, Bowes, Georgia, Rheaume, John, Chapman, Rebecca, Ramage, Judith, Jackson, Andrew, Grundy, Richard, Foreman, Nicholas, Ritzmann, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165116/
http://dx.doi.org/10.1093/neuonc/noac079.303