DIPG-47. TSO500ctDNA sequencing reveals oncogenic mutations and copy number variations in the liquid biome of children with diffuse midline glioma

BACKGROUND: Molecular profiling of childhood CNS tumors is critical for diagnosis and clinical management, yet tissue access is restricted due to sensitive neuroanatomical locations. Moreover, CNS tumors including diffuse midline glioma (DMG) exhibit mutational heterogeneity and clonal evolution, wh...

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Detalles Bibliográficos
Autores principales: Bonner, Erin R, Harrington, Robin, Eze, Augustine, Bornhorst, Miriam, Kline, Cassie N, Dawood, Adam, Das, Biswajit, Chen, Li, Pauly, Rini, Williams, P Mickey, Karlovich, Chris, Peach, Amanda, Howell, D'Andra, Doroshow, James, Kilburn, Lindsay, Packer, Roger J, Mueller, Sabine, Nazarian, Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Diffuse Midline Glioma/DIPG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165125/
http://dx.doi.org/10.1093/neuonc/noac079.104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165125/
http://dx.doi.org/10.1093/neuonc/noac079.104

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