DIPG-06. Uncovering the FACTs in Diffuse Midline Glioma (DMG)

Effective treatments are urgently needed for the incurable paediatric brainstem tumour Diffuse Midline Glioma (DMG). Most DMGs contain Histone H3 mutations (H3K27M), which produce extensive epigenetic dysregulation by inhibiting EZH2-mediated trimethylation of H3K27 (H3K27me3). Global depletion of t...

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Detalles Bibliográficos
Autores principales: Holliday, Holly, Ehteda, Anahid, Khan, Aaminah, Krug, Brian, Rouaen, Jourdin R C, Jayatilleke, Nisitha, Mayoh, Chelsea, Vittorio, Orazio, Jabado, Nada, Tsoli, Maria, Ziegler, David S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Diffuse Midline Glioma/DIPG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165134/
http://dx.doi.org/10.1093/neuonc/noac079.063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165134/
http://dx.doi.org/10.1093/neuonc/noac079.063

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