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MEDB-69. Clinical and molecular meta-analysis of three major medulloblastoma clinical trials (ACNS0331, SJMB03, ACNS0332) uncovers novel strategies to improve risk-stratified therapy

BACKGROUND: Given the vast molecular heterogeneity present within medulloblastoma (MB) and considerable differences in therapy, we performed a meta-analysis of three large, recently published, prospective clinical trials (ACNS0331, SJMB03, ACNS0332) comprising 898 children with newly-diagnosed MB to...

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Detalles Bibliográficos
Autores principales: Smith, Kyle S, Billups, Catherine A, Dhanda, Sandeep K, Bihannic, Laure, Vasilyeva, Aksana, Li, Yimei, Michalski, Jeff M, Olsen, James M, Leary, Sarah, Fouladi, Maryam, Gajjar, Amar, Onar, Arzu, Northcott, Paul A, Robinson, Giles W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165139/
http://dx.doi.org/10.1093/neuonc/noac079.443