IMMU-22. Safely targeting GD2 in thalamic diffuse midline glioma with mRNA CAR T cells

Chimeric antigen receptor (CAR) T cells targeting the disialoganglioside GD2 have shown promise as a therapeutic for diffuse midline glioma (DMG). However, prior studies raised significant concerns of neurotoxicity and fatality when using virally transduced CAR T cells against midline thalamic tumor...

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Detalles Bibliográficos
Autores principales: Foster, Jessica, Griffin, Crystal, Stern, Allison, Madsen, Peter, Storm, Phillip, Resnick, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165178/
http://dx.doi.org/10.1093/neuonc/noac079.315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165178/
http://dx.doi.org/10.1093/neuonc/noac079.315

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