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IMMU-22. Safely targeting GD2 in thalamic diffuse midline glioma with mRNA CAR T cells
Chimeric antigen receptor (CAR) T cells targeting the disialoganglioside GD2 have shown promise as a therapeutic for diffuse midline glioma (DMG). However, prior studies raised significant concerns of neurotoxicity and fatality when using virally transduced CAR T cells against midline thalamic tumor...
Autores principales: | Foster, Jessica, Griffin, Crystal, Stern, Allison, Madsen, Peter, Storm, Phillip, Resnick, Adam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165178/ http://dx.doi.org/10.1093/neuonc/noac079.315 |
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