LGG-48. The influence of different FGFR1 alterations on pediatric low-grade glioma tumor biology and targeted therapy response

Pediatric low-grade gliomas (pLGGs) have excellent survival, however, with current standard of care, most patients suffer lifelong severe sequalae. pLGGs are almost exclusively driven by single activating mutations in the MAPK pathway. Clinical trials with small molecule inhibitors in BRAF-altered p...

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Detalles Bibliográficos
Autores principales: Morin, Eric, DiGiacomo, Jeromy, Novikov, Dana, Malinowski, Seth, Chow, Kin-Hoe, Jones, David, Alexandrescu, Sanda, Ligon, Keith, Bandopadhayay, Pratiti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Low Grade Glioma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165226/
http://dx.doi.org/10.1093/neuonc/noac079.360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165226/
http://dx.doi.org/10.1093/neuonc/noac079.360

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