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MEDB-80. CDK8 promotes stemness of MYC-driven medulloblastoma

Cyclin-dependent kinase 8 (CDK8) belongs to the transcription-related cyclin dependent protein kinase family. CDK8 and cyclin C associate with the mediator complex to regulate gene transcription. Although CDK8 has been shown to be implicated in the malignancy of several types of cancer, its function...

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Detalles Bibliográficos
Autores principales: Wang, Dong, Veo, Bethany, Pierce, Angela, Venkataraman, Sujatha, Vibhakar, Rajeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165241/
http://dx.doi.org/10.1093/neuonc/noac079.454