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LGG-42. Thromboembolic toxicity observed with concurrent trametinib and lenalidomide therapy

INTRODUCTION: Event-free survival of pediatric low-grade glioma (pLGG) is poor, and patients often require multiple treatment strategies. The hallmark of pLGGs are genetic aberrations of the mitogen-activated protein kinase pathway, which lead to constitutive pathway activation. MEK and RAF inhibito...

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Detalles Bibliográficos
Autores principales: Chan, Priya, Sabus, Ashley, Hemenway, Molly, Chatfield, Kathryn, Foreman, Nicholas, Dahl, Nathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165242/
http://dx.doi.org/10.1093/neuonc/noac079.354