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Amyotrophic lateral sclerosis with SOD1 mutations shows distinct brain metabolic changes

PURPOSE: Neuropathological data suggest that ALS with SOD1 mutations (SOD1-ALS) is a distinct form of ALS. We evaluated brain metabolic changes characterizing SOD1-ALS as compared to sporadic ALS (sALS), employing (18)fluorodeoxyglucose-positron-emission tomography ((18)F-FDG-PET). METHODS: We inclu...

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Detalles Bibliográficos
Autores principales: Canosa, Antonio, Calvo, Andrea, Moglia, Cristina, Vasta, Rosario, Palumbo, Francesca, Solero, Luca, Di Pede, Francesca, Cabras, Sara, Arena, Vincenzo, Zocco, Grazia, Casale, Federico, Brunetti, Maura, Sbaiz, Luca, Gallone, Salvatore, Grassano, Maurizio, Manera, Umberto, Pagani, Marco, Chiò, Adriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165265/
https://www.ncbi.nlm.nih.gov/pubmed/35076740
http://dx.doi.org/10.1007/s00259-021-05668-7