Cargando…

Amyotrophic lateral sclerosis with SOD1 mutations shows distinct brain metabolic changes

PURPOSE: Neuropathological data suggest that ALS with SOD1 mutations (SOD1-ALS) is a distinct form of ALS. We evaluated brain metabolic changes characterizing SOD1-ALS as compared to sporadic ALS (sALS), employing (18)fluorodeoxyglucose-positron-emission tomography ((18)F-FDG-PET). METHODS: We inclu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Canosa, Antonio, Calvo, Andrea, Moglia, Cristina, Vasta, Rosario, Palumbo, Francesca, Solero, Luca, Di Pede, Francesca, Cabras, Sara, Arena, Vincenzo, Zocco, Grazia, Casale, Federico, Brunetti, Maura, Sbaiz, Luca, Gallone, Salvatore, Grassano, Maurizio, Manera, Umberto, Pagani, Marco, Chiò, Adriano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165265/ https://www.ncbi.nlm.nih.gov/pubmed/35076740 http://dx.doi.org/10.1007/s00259-021-05668-7

Ejemplares similares

GBA variants influence cognitive status in amyotrophic lateral sclerosis
por: Canosa, Antonio, et al.
Publicado: (2022)

Role of brain 2-[(18)F]fluoro-2-deoxy-D-glucose-positron-emission tomography as survival predictor in amyotrophic lateral sclerosis
por: Canosa, Antonio, et al.
Publicado: (2022)

Phenotype Analysis of Fused in Sarcoma Mutations in Amyotrophic Lateral Sclerosis
por: Grassano, Maurizio, et al.
Publicado: (2022)

Brain metabolic changes across King’s stages in amyotrophic lateral sclerosis: a (18)F-2-fluoro-2-deoxy-d-glucose-positron emission tomography study
por: Canosa, Antonio, et al.
Publicado: (2020)

Clinical and Metabolic Signature of UNC13A rs12608932 Variant in Amyotrophic Lateral Sclerosis
por: Calvo, Andrea, et al.
Publicado: (2022)

Social cognition deficits in amyotrophic lateral sclerosis: A pilot cross‐sectional population‐based study
por: Palumbo, Francesca, et al.
Publicado: (2022)

The Characteristics of Cognitive Impairment in ALS Patients Depend on the Lateralization of Motor Damage
por: Manera, Umberto, et al.
Publicado: (2020)

Amyotrophic lateral sclerosis patients' quality of life and their caregiver burden during COVID-19 pandemic
por: Bombaci, Alessandro, et al.
Publicado: (2021)

Serum chloride as a respiratory failure marker in amyotrophic lateral sclerosis
por: Manera, Umberto, et al.
Publicado: (2023)

Brain metabolic differences between pure bulbar and pure spinal ALS: a 2-[(18)F]FDG-PET study
por: Canosa, Antonio, et al.
Publicado: (2022)

Systematic evaluation of genetic mutations in ALS: a population-based study
por: Grassano, Maurizio, et al.
Publicado: (2022)

The role of peripheral immunity in ALS: a population‐based study
por: Grassano, Maurizio, et al.
Publicado: (2023)

Respiratory support in a population-based ALS cohort: demographic, timing and survival determinants
por: Chio, Adriano, et al.
Publicado: (2022)

Lifetime sport practice and brain metabolism in Amyotrophic Lateral Sclerosis
por: Canosa, Antonio, et al.
Publicado: (2020)

Effects of intracellular calcium accumulation on proteins encoded by the major genes underlying amyotrophic lateral sclerosis
por: De Marco, Giovanni, et al.
Publicado: (2022)

Exploring the phenotype of Italian patients with ALS with intermediate ATXN2 polyQ repeats
por: Chio, Adriano, et al.
Publicado: (2022)

Presymptomatic geographical distribution of ALS patients suggests the involvement of environmental factors in the disease pathogenesis
por: Vasta, Rosario, et al.
Publicado: (2023)

Plasma CHI3L1 in Amyotrophic Lateral Sclerosis: A Potential Differential Diagnostic Biomarker
por: Bombaci, Alessandro, et al.
Publicado: (2023)

The links between diabetes mellitus and amyotrophic lateral sclerosis
por: Vasta, Rosario, et al.
Publicado: (2021)

A Dynamic Bayesian Network model for the simulation of Amyotrophic Lateral Sclerosis progression
por: Zandonà, Alessandro, et al.
Publicado: (2019)

Withdrawal of mechanical ventilation in amyotrophic lateral sclerosis patients: a multicenter Italian survey
por: Moglia, Cristina, et al.
Publicado: (2023)

Defective cyclophilin A induces TDP-43 proteinopathy: implications for amyotrophic lateral sclerosis and frontotemporal dementia
por: Pasetto, Laura, et al.
Publicado: (2021)

The transcription factor Nurr1 is upregulated in amyotrophic lateral sclerosis patients and SOD1-G93A mice
por: Valsecchi, Valeria, et al.
Publicado: (2020)

Predicting functional impairment trajectories in amyotrophic lateral sclerosis: a probabilistic, multifactorial model of disease progression
por: Tavazzi, Erica, et al.
Publicado: (2022)

The HFE p.H63D (p.His63Asp) Polymorphism Is a Modifier of ALS Outcome in Italian and French Patients with SOD1 Mutations
por: Canosa, Antonio, et al.
Publicado: (2023)

SOD1 in Amyotrophic Lateral Sclerosis: “Ambivalent” Behavior Connected to the Disease
por: Pansarasa, Orietta, et al.
Publicado: (2018)

SOD1 misplacing and mitochondrial dysfunction in amyotrophic lateral sclerosis pathogenesis
por: Tafuri, Francesco, et al.
Publicado: (2015)

Deep learning methods to predict amyotrophic lateral sclerosis disease progression
por: Pancotti, Corrado, et al.
Publicado: (2022)

SOMAscan Proteomics Identifies Novel Plasma Proteins in Amyotrophic Lateral Sclerosis Patients
por: Berrone, Elena, et al.
Publicado: (2023)

Untangling the knot: Lifetime physical exercise and amyotrophic lateral sclerosis
por: Chiò, Adriano, et al.
Publicado: (2021)

G-CSF (filgrastim) treatment for amyotrophic lateral sclerosis: protocol for a phase II randomised, double-blind, placebo-controlled, parallel group, multicentre clinical study (STEMALS-II trial)
por: Salamone, Paolina, et al.
Publicado: (2020)

SOD-1 Variants in Amyotrophic Lateral Sclerosis: Systematic Re-Evaluation According to ACMG-AMP Guidelines
por: Ruffo, Paola, et al.
Publicado: (2022)

SOD1 and Amyotrophic Lateral Sclerosis: Mutations and Oligomerization
por: Banci, Lucia, et al.
Publicado: (2008)

Metal-deficient SOD1 in amyotrophic lateral sclerosis
por: Hilton, James B., et al.
Publicado: (2015)

A PET/CT approach to spinal cord metabolism in amyotrophic lateral sclerosis
por: Marini, Cecilia, et al.
Publicado: (2016)

Interplay between spinal cord and cerebral cortex metabolism in amyotrophic lateral sclerosis
por: Marini, Cecilia, et al.
Publicado: (2018)

The multistep hypothesis of ALS revisited: The role of genetic mutations
por: Chiò, Adriano, et al.
Publicado: (2018)

Altered Intracellular Localization of SOD1 in Leukocytes from Patients with Sporadic Amyotrophic Lateral Sclerosis
por: Cereda, Cristina, et al.
Publicado: (2013)

Is SOD1 loss of function involved in amyotrophic lateral sclerosis?
por: Saccon, Rachele A., et al.
Publicado: (2013)

Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis
por: Paré, Bastien, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_vgn2jpd3vvfkv9kc5km2onra9b