Characterization in nonhuman primates of (R)-[(18)F]OF-Me-NB1 and (S)-[(18)F]OF-Me-NB1 for imaging the GluN2B subunits of the NMDA receptor

PURPOSE: GluN2B containing N-methyl-D-aspartate receptors (NMDARs) play an essential role in neurotransmission and are a potential treatment target for multiple neurological and neurodegenerative diseases, including stroke, Alzheimer’s disease, and Parkinson’s disease. (R)-[(18)F]OF-Me-NB1 was repor...

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Detalles Bibliográficos
Autores principales: Zheng, MingQiang, Ahmed, Hazem, Smart, Kelly, Xu, Yuping, Holden, Daniel, Kapinos, Michael, Felchner, Zachary, Haider, Ahmed, Tamagnan, Gilles, Carson, Richard E., Huang, Yiyun, Ametamey, Simon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165293/
https://www.ncbi.nlm.nih.gov/pubmed/35107627
http://dx.doi.org/10.1007/s00259-022-05698-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165293/
https://www.ncbi.nlm.nih.gov/pubmed/35107627
http://dx.doi.org/10.1007/s00259-022-05698-9

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