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Characterization in nonhuman primates of (R)-[(18)F]OF-Me-NB1 and (S)-[(18)F]OF-Me-NB1 for imaging the GluN2B subunits of the NMDA receptor
PURPOSE: GluN2B containing N-methyl-D-aspartate receptors (NMDARs) play an essential role in neurotransmission and are a potential treatment target for multiple neurological and neurodegenerative diseases, including stroke, Alzheimer’s disease, and Parkinson’s disease. (R)-[(18)F]OF-Me-NB1 was repor...
Autores principales: | Zheng, MingQiang, Ahmed, Hazem, Smart, Kelly, Xu, Yuping, Holden, Daniel, Kapinos, Michael, Felchner, Zachary, Haider, Ahmed, Tamagnan, Gilles, Carson, Richard E., Huang, Yiyun, Ametamey, Simon M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165293/ https://www.ncbi.nlm.nih.gov/pubmed/35107627 http://dx.doi.org/10.1007/s00259-022-05698-9 |
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