DIPG-11. DIPGs show robust MHC class I expression but low lymphoid and high myeloid infiltration partly reversible by DNA methyltransferase inhibition

Diffuse intrinsic pontine gliomas (DIPGs) are the most aggressive tumors of the central nervous system in children. Median survival of patients is less than one year post-diagnosis. Radiotherapy remains the only standard treatment but is rarely curative. Immunotherapy is an emerging and promising tr...

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Detalles Bibliográficos
Autores principales: Mishra, Deepak, Wang, Jie, Chen, Chun-Yu, Zhu, Xiaoting, Kumar, Shiva Senthil, McHugh, Todd, Cripe, Timothy, Fouladi, Maryam, Drissi, Rachid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Diffuse Midline Glioma/DIPG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165300/
http://dx.doi.org/10.1093/neuonc/noac079.068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165300/
http://dx.doi.org/10.1093/neuonc/noac079.068

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