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RARE-08. Profiling of recurrent adamantinomatous cranionpharyngioma confirms the activation of the MAPK pathway and identifies copy number aberrations in relapsed tumours

Craniopharyngiomas are rare challenging tumours, with around 25% of cases recurring despite surgery and/or radiotherapy. Whilst transcriptomic and proteomic profiling of adamantinomatous craniopharyngioma (ACP) have revealed activation of the MAPK pathway and IL-6 mediated inflammation, relatively l...

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Detalles Bibliográficos
Autores principales: Apps, John, Pickles, Jessica, Stone, Thomas, Chalker, Jane, Ogunbiyi, Olumide, Schwalbe, Edward, Brandner, Sebastian, Otto, Georg, Castellano, Sergi, Jacques, Thomas, Deutschbein, Timo, Martinez-Barbera, Juan Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165309/
http://dx.doi.org/10.1093/neuonc/noac079.033