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ETMR-05. Single-cell transcriptomics of ETMR reveals developmental cellular programs and tumor-pericyte communications in the microenvironment

BACKGROUND: Embryonal tumors with multilayered rosettes (ETMR) are pediatric brain tumors bearing a grim prognosis, despite intensive multimodal therapeutic approaches. Insights into cellular heterogeneity and cellular communication of tumor cells with cells of the tumor microenvironment (TME), by a...

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Detalles Bibliográficos
Autores principales: de Faria, Flavia W, Walter, Carolin, Interlandi, Marta, Melcher, Viktoria, Riedel, Nicole, Graf, Monika, Moreno, Natalia, Schoof, Melanie, Holdhof, Dörthe, Thomas, Christian, Frühwald, Michael C, Maerkl, Bruno, Ho, Ben, Sandmann, Sarah, Varghese, Julian, Ebinger, Martin, Schuhmann, Martin, Canak, Aysegül, Huang, Annie, Schüller, Ulrich, Albert, Thomas K, Kerl, Kornelius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165314/
http://dx.doi.org/10.1093/neuonc/noac079.183