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DIPG-49. International preclinical drug discovery and biomarker program informing an adoptive combinatorial trial for DMG

INTRODUCTION: DMG-ACT (DMG- multi-arm Adaptive and Combinatorial Trial) will implement an innovative clinical trial design of combinatorial arms for patients with DMG at all disease stages, that is adaptive to pre-clinical and correlate data generated in eight collaborating institutions. The goal of...

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Detalles Bibliográficos
Autores principales: Nazarian, Javad, Dun, Matthew, Kilburn, Lindsay, Waszak, Sebastian, Vitanza, Nicholas, Franson, Andrea, Prados, Mike, Raabe, Eric, Firestein, Ron, Beck, Alexander, Saratsis, Amanda, Rotblat, Barak, van Vuurder, Dannis, Foster, Jessica, Hulleman, Esther, Kline, Cassie, Gupta, Nalin, Cain, Jason, Koschmann, Carl, Muller, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165348/
http://dx.doi.org/10.1093/neuonc/noac079.106