HGG-10. Efficacy of convection-enhanced delivery of GB-13 (IL13.E13K-PE4E) in an orthotopic xenograft model of high-grade glioma is predicated on IL-13Rα2 expression.

High-grade gliomas (HGG) encompass a large proportion of malignant tumors within the central nervous system. Despite advances in our understanding of underlying disease mechanisms, the prognosis remains dismal and efficacious therapies are lacking. As such, there is a dire, unmet, gap in clinical pr...

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Detalles Bibliográficos
Autores principales: Rechberger, Julian, Porath, Kendra, Schrecengost, Randy, Sarkaria, Jann, Daniels, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
High Grade Glioma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165356/
http://dx.doi.org/10.1093/neuonc/noac079.225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165356/
http://dx.doi.org/10.1093/neuonc/noac079.225

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