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NR4A1 agonist cytosporone B attenuates neuroinflammation in a mouse model of multiple sclerosis

Nuclear receptor subfamily 4 group A1 (NR4A1) is an orphan nuclear receptor, which is expressed in the majority of cells. NR4A1 expression in peripheral blood mononuclear cells is low during the preclinical stage of multiple sclerosis. Knockout of the Nr4a1 gene in mice can aggravate the symptoms of...

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Detalles Bibliográficos
Autores principales: Yu, Hai-Zhen, Zhu, Bing-Qing, Zhu, Lin, Li, Shuo, Wang, Li-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165396/
https://www.ncbi.nlm.nih.gov/pubmed/35662227
http://dx.doi.org/10.4103/1673-5374.339492