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Disrupting Osr1 expression promoted hepatic steatosis and inflammation induced by high-fat diet in the mouse model

NAFLD, regarded as the hepatic manifestation of metabolic syndrome, is the most common form of liver disease in the United States. The Odd-skipped related 1 (Osr1) gene was previously reported to play a critical role in embryonic development and as a cancer repressor gene, however its role in overnu...

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Detalles Bibliográficos
Autores principales: Lynch, Ernest C., Liu, Zhimin, Liu, Lin, Wang, Xian, Zhang, Ke K., Xie, Linglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165803/
https://www.ncbi.nlm.nih.gov/pubmed/35657825
http://dx.doi.org/10.1371/journal.pone.0268344